Contact us at (800) USC-CARE (800-872-2273)
USC Center for Advanced Lung Disease2020-01-09T18:41:17+00:00
Affiliated with the division of pulmonary, critical care and sleep medicine, the USC Center for Advanced Lung Disease is dedicated to helping patients to breathe easier, live longer and enjoy a better quality of life by providing excellent, innovative and patient-centered care. Our lung experts provide highly specialized evaluations and treatment options for all patients suffering from complex lung diseases, regardless of their transplant status. Referring physicians have rapid access to physicians who offer vast experience in treating the most severe cases of advanced lung disease.

Our personalized interdisciplinary approach consists of many specialties, such as infectious disease, thoracic surgery, endocrinology, cardiology, rheumatology, gastroenterology, pathology, radiology, otolaryngology, physical therapy and transplant when appropriate. The result is comprehensive and individualized diagnostic and treatment plans that produce optimal outcomes.

Patients who are referred to the USC Center for Advanced Lung Disease have access to the resources of a leading academic medical center. We support patients and families throughout care, from managing complex conditions to providing life support within four intensive care units at the Keck Medical Center at USC. Patients also benefit from a robust clinical research program that provides access to cutting-edge procedures, technologies and therapies. Our focus on innovation includes active participation in patient safety and quality improvement programs that enable us to provide an exceptional experience for patients and their families.

We evaluate and encourage referrals of patients with any form of advanced lung disease including conditions such as:

  • Interstitial lung disease
  • Rare lung diseases
  • Sarcoidosis
  • Cystic fibrosis
  • Severe asthma
  • Chronic obstructive pulmonary disease (COPD)
  • Sleep-disordered breathing
  • Pulmonary hypertension
Looking for information about lung cancer? Visit the USC Lung Cancer Program page for more information and details about a low-cost lung cancer screening.

Our Location

USC Department of Medicine
1500 San Pablo Street, 3 North Clinic
Los Angeles, CA 90033

To make an appointment or refer a patient please contact:

Tel: (800) USC-CARE (800-872-2273)
Fax: (323) 865-9208

USC Division of Pulmonary, Critical Care and Sleep Medicine

The Division of Pulmonary, Critical Care and Sleep Medicine provides a vigorous and creative basic and clinical science core, an active clinical service, and a high quality teaching program. Led by Zea Borok, MD, the division counts over 20 full-time faculty members with national and international reputations who share a combined research, clinical and teaching mission.The division prides itself on the quality, depth and breadth of its clinical services. Patient and colleague satisfaction, along with state-of-the-art pulmonary and critical care medicine services, remain our primary clinical objectives.


The USC Center for Advanced Lung Disease brings together all the unique resources needed for treating even the most challenging lung diseases.

Our specialists use innovative procedures and state-of-the-art technology to deliver exceptional outcomes. To reduce risk and expedite recovery we offer many noninvasive procedures highlighted below.

  • Endobronchial Ultrasound (EBUS) Biopsy provides imaging of airway walls, lymph nodes and surrounding vessels to enhance diagnosis of lung cancer, infections, and other diseases causing enlarged lymph nodes in the chest. EBUS makes biopsies safer and more accurate than conventional “blind” needle aspiration.
  • Bronchial Thermoplasty, a breakthrough in treating severed uncontrolled asthma, was tested in clinical trials at the Keck Medical Center of USC. It achieved a 32 percent reduction in asthma attacks after treatment. Bronchial thermoplasty uses a catheter to deliver radiofrequency energy to airway walls to reduce excessive airway smooth muscle. The outpatient procedure is performed under moderate sedation, so patients usually return home the same day with a significant and lasting improvement to their quality of life.
  • Endobronchial One-way Valve Replacement is used to treat and manage hyperinflation in emphysematous lungs by placing specialized valves in segments of the bronchi leading to diseased areas. The one-way function allows for lung deflation, reduces hyperexpansion and improves symptoms.
  • Bronchoscopic Balloon Dilation employs angioplasty balloon catheters in affected airways to relieve bronchial stenosis.
  • Endobronchial Stent Deployment is used to treat strictures, collapse, communication between the trachea and esophagus and tumors.
  • Bronchoscopic Laser Resection utilizes Argon laser therapies to relieve airway obstruction from prolonged intubation, web-like strictures and tumors.

Advantages of the USC Center for Advanced Lung Disease:

  • Expertise in Complex and Difficult Cases
  • Access to Highly Experienced Clinicians
  • Interdisciplinary, Patient-centered Care
  • Full Continuum of Care
  • Focus on Patient Safety and Quality Improvement
  • Robust Clinical Research Program
Every patient coming to USC is seen by a board certified pulmonologist who conducts a comprehensive patient evaluation, provides a diagnosis, and explains the best treatment options. Each patient will receive a personalized tailored plan of care that considers all aspects of patient care needs.

Patient Testimonials

Cathleen Bartleson was disappointed when she was told that she had no alternative except to deal with the limitations imposed by her COPD. Despite a prescribed regimen of steroids and breathing exercises, her shortness of breath and severe coughing episodes were worsening. She could no longer work as a substitute teacher. Looking for answers, Cathleen came to the USC Center for Advanced Lung Disease.

Initially she consulted with USC cardiothoracic surgeon, Paul M. McFadden, MD, in hopes that lung volume reduction surgery could help. After a brief evaluation, he referred Cathleen to the USC Center for Advanced Lung Disease. After some tests, Cathleen’s doctor adjusted medications and developed an exercise schedule. He continues to monitor her condition and is exploring her participation in a clinical trial.

Before I started going to USC, I was hopeless. Now, I have hope.” ~ Cathleen Bartleson

Relief from Sarcoidosis

Beatrice Aleman from Paramount, California, has struggled with the symptoms of sarcoidosis for more than a decade. When a severe coughing episode brought up blood, her husband took her to the emergency department of a local hospital. Physicians stopped the bleeding and referred her to Dr. Kamyar Afshar at USC.

The care team at the USC Center for Advanced Lung Disease reviewed her medical history, conducted evaluations and developed a treatment plan that provided careful follow-up. Her treatment included prescribing a different antifungal medication and providing relief from pain. As a result, Beatrice’s incessant coughing has subsided, and her pain scale is now at a very manageable level.

“Dr. Afshar takes the time to listen and find out how I feel. All my fears and anxieties go away. Now I can continue.” ~ Beatrice Aleman

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Practicing Locations

Keck Hospital of USC
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Practicing Locations

Keck Hospital of USC
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Practicing Locations

Keck Hospital of USC
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Practicing Locations

Keck Hospital of USC
USC Healthcare Center 2
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Book Online with Zocdoc

Practicing Locations

Keck Hospital of USC
Keck Medicine of USC is the University of Southern California’s medical enterprise, one of only two university-owned academic medical centers in the Los Angeles area.